Cancer BiologybioRxivPreprint
Spatial multi-omics analysis reveals vimentin-high macrophages-endothelial cells niche shapes CAFs heterogeneity in colorectal cancer metastasis
Mingzhou Li, Bingyu Xu, Jieqiong Wu…·Liang Li
The paper identifies a vimentin-high macrophages-endothelial niche that drives CAF heterogeneity in CRC metastasis, with distinct signaling pathways in primary tumors and liver metastases.
DOI 10.64898/2026.08.26.747355