Mingzhou Li

The paper uses RIC-seq and integrates multi-omics data to classify transcription factors into two clusters based on RNA-RNA spatial interactions and their genomic and clinical features.

The paper identifies a vimentin-high macrophages-endothelial niche that drives CAF heterogeneity in CRC metastasis, with distinct signaling pathways in primary tumors and liver metastases.

This study shows miR-486-3p improves angiogenesis in Moyamoya disease by targeting FOXO4 to reduce senescence-associated secretory phenotype.

The paper presents PigGTEx, a resource linking genetic variants to transcriptomic phenotypes in pigs, showing pigs' similarity to humans in gene regulation and complex traits.

The paper investigates 3D chromatin structural changes during spermatogonial differentiation in pigs using Hi-C, RNA-seq, and ChIP-seq, revealing altered chromatin architecture and gene regulation.

The paper constructs a pig pan-genome using multiple de novo assemblies and Hi-C data, identifying novel sequences and improving SNP calling for genetic diversity analysis.

The paper analyzes genomic and transcriptomic data from DLY pigs to identify breed-of-origin SNPs and ASE genes, suggesting their role in improved performance and genetic architecture of three-way crossbreeding.