Diamante Boscaro

Ultra-structural analysis of mineralized extracellular matrix in osteogenic monolayers and spheroids: comparison of sample preparation methods

This study compares two TEM sample preparation methods for preserving mineralized ECM in osteogenic cells, finding that chemical fixation better preserves mineral deposits in 3D spheroids.

Label-free imaging of matrix mineralization in alginate-encapsulated bone spheroids using Coherent Raman Scattering microscopy

This study uses Coherent Raman Scattering microscopy to characterize matrix mineralization in 3D bone spheroids without labels, showing its effectiveness in detecting phosphate and collagen structures.

Characterization of ECM produced by MC3T3-E1 cellular spheroids encapsulated in alginate hydrogel

This study characterizes the extracellular matrix (ECM) produced by MC3T3-E1 spheroids in alginate hydrogel, showing collagen deposition between week 2 and 4.