Programmable domestication of thermophilic bacteria through removal of non-canonical defense systems
Jae‐Yoon Sung, Mun‐Hoe Lee, Jungsoo Park, Hyungbin Kim, Dariimaa Ganbat, Dong-Gyu Kim, Hyun-Woo Cho, Min Kuk Suh, Jung‐Sook Lee, Sang-Jae Lee, Seong-Bo Kim, Dong‐Woo Lee
This paper develops a method to make thermophilic bacteria genetically tractable by removing non-canonical defense systems, enabling stable genetic modification at high temperatures.
bioRxiv · Mar 24, 2026 · PreprintBioengineering