Author

Ruchir R

Indian Institute of Technology MadrasORCID 0009-0004-8341-4600Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

Ana Ciochina· 1 shared Edene Levine· 1 shared Karthik Raman· 1 shared Srikrishnan Balamuhunthan· 1 shared Wilma Roch· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperBioinformatics

Ana Ciochina

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2 papers

Recent·Most cited

Generative Models for Novel Enzymatic Reactions: How Far Do They Go?

Ruchir R, Srikrishnan Balamuhunthan, Karthik Raman

This paper evaluates generative models for predicting novel enzymatic reactions, finding they can generate correct reactions for 25% of test cases and improve over existing methods.

bioRxiv · Nov 6, 2026 · PreprintBioinformatics

Computational Profiling and Pathogenicity Assessment of VHL Missense Mutations

Ruchir R, Edene Levine, Wilma Roch, Ana Ciochina

This study assesses the pathogenicity of VHL missense mutations using AlphaMissense, protein stability simulations, and molecular dynamics to identify critical regions and mutation effects.

bioRxiv · Oct 22, 2026 · PreprintBioinformatics