Author

Rebecca Chae

University of PennsylvaniaORCID 0009-0004-8622-6429Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Ge Liang· 2 shared Huafeng WeiiD· 2 shared Kyulee KimiD· 2 shared Lauren St. Louis· 2 shared Piplu BhuiyaniD· 2 shared Wenjia ZhangiD· 2 shared Ying Wang· 2 shared Bailin JiangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Ge Liang

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2 papers

Recent·Most cited

Intranasal Delivery of Lithium Salt Suppresses Inflammatory Pyroptosis in the brain and Ameliorates Memory Loss and Depression-like Behavior in 5XFAD mice

Piplu Bhuiyan, Wenjia Zhang, Ge Liang, Bailin Jiang, Robert Vera, Rebecca Chae, Kyulee Kim, Lauren St. Louis, Ying Wang, Jia Liu, De‐Maw Chuang, Huafeng Wei

This study shows that intranasal lithium salt delivery in RFV reduces brain inflammation and pyroptosis, improves memory and depression-like behaviors in 5XFAD mice, with minimal side effects.

Journal of Neuroimmune Pharmacology · Mar 17, 2025Peer-reviewedNeuroscience

Intranasal dantrolene nanoparticles inhibit inflammatory pyroptosis in 5XFAD mice brains

Piplu Bhuiyan, Wenjia Zhang, Rebecca Chae, Kyulee Kim, Lauren St. Louis, Ying Wang, Ge Liang, Huafeng Wei

This study shows that intranasal dantrolene nanoparticles reduce pyroptosis and inflammation in 5XFAD mice brains without affecting organ function or body weight.

bioRxiv · Nov 25, 2024 · PreprintNeuroscience