Author

Wan-Chi Chang

Cincinnati Children's Hospital Medical CenterORCID 0009-0004-9775-928XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Amal Assa’adiD· 1 shared Asel Baatyrbek kyzy· 1 shared Ashley Lynn DevonshireiD· 1 shared Carolina MooreiD· 1 shared Emily R. MiraldiiD· 1 shared Gurjit K. Khurana HersheyiD· 1 shared Jeff W. BurkleiD· 1 shared Jocelyn M. Biagini MyersiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Amal Assa’adORCID

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1 paper

Recent·Most cited

Use of Antibody Structural Information in Disease Prediction Models Reveals Antigen Specific B Cell Receptor Sequences in Bulk Repertoire Data

Onyekachi Nwogu, Kirandeep K. Gill, Carolina Moore, John W. Kroner, Wan-Chi Chang, Jeff W. Burkle, Mariana L. Stevens, Asel Baatyrbek kyzy, Emily R. Miraldi, Jocelyn M. Biagini Myers, Ashley Lynn Devonshire, Leah Claire Kottyan, Justin T. Schwartz, Amal Assa’ad, Lisa Joy Martin, , Krishna M. Roskin

This study uses structural information of antibodies to identify convergent antibodies in bulk IgH data, improving disease prediction for food sensitization and matching HIV prediction performance.

bioRxiv · Dec 10, 2024 · PreprintImmunology