NeurosciencebioRxivPreprint
Detecting time-varying genetic effects in Alzheimer's disease using a longitudinal GWAS model
Xiaowei Zhuang, Gang Xu, Amei Amei…·Alzheimer’s Disease Neuroimaging Initiative
This paper develops a longitudinal GWAS model with time-varying coefficients to detect genetic effects in Alzheimer's disease, identifying SNPs with age-dependent effects on clinical and biological phenotypes.
DOI 10.1101/2023.10.17.562756