Author

Shize Yu

Huazhong University of Science and TechnologyORCID 0009-0005-0448-9055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein sequence· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Yunxin XuiD· 2 shared Ziyu ShiiD· 2 shared Endi YangiD· 1 shared Haipeng GongiD· 1 shared Jian HuiD· 1 shared Mengxin YangiD· 1 shared Weizhe WangiD· 1 shared Yancheng ShiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

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2 shared papersBioinformatics

Yunxin XuORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 24, 2026

From single-sequence structure prediction to protein fitness landscape through a composable, epistasis-aware mutation atlas

Weizhe Wang, Zimu Yu, Endi Yang…·Haipeng Gong

The paper introduces Cerebra-Epistasis, a framework that improves multi-mutant fitness prediction by modeling epistatic effects and integrating structure-aware sequence analysis.

DOI 10.64898/2026.09.24.753701

protein sequencedeep learning

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BioinformaticsbioRxivPreprintSep 24, 2026

MutCleaner: Cleaning and Standardizing Biological Mutation Datasets for Variant Effect Prediction

Ziyu Shi, Yuxiang Tang, Mengxin Yang…·Yunxin Xu

MutCleaner standardizes mutation datasets for variant effect prediction by cleaning, validating, and organizing mutation records across 16 datasets with over 12.14 million entries.

DOI 10.64898/2026.09.06.749687

protein sequencestatistical model

𝕏 PostBluesky