Author

Hugo Chenel

Centre National de la Recherche ScientifiqueORCID 0009-0005-2852-6818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Loïc YsebaertiD· 2 shared Malvina MarkuiD· 2 shared Marcelo HurtadoiD· 2 shared Véra PancaldiiD· 2 shared Andrei Y. ZinovyeviD· 1 shared Cécile PineauiD· 1 shared Étienne ChatelutiD· 1 shared Flavien RaynaliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 36 mutual co-author links

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2 shared papersSystems Biology

Loïc YsebaertORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 28, 2026

A multiscale pharmacokinetic-Boolean modelling framework for ibrutinib resistance in a Chronic Lymphocytic Leukaemia case study

Malvina Marku, Cécile Pineau, Miguel Hurtado…·Mélanie White‐Koning

This paper develops a multiscale framework linking pharmacokinetics and Boolean models to study ibrutinib resistance in CLL, identifying key regulons and synergistic targets.

DOI 10.64898/2026.10.26.759125

humanstatistical model

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Systems BiologybioRxivPreprintApr 20, 2025

Time-series RNA-Seq and data-driven network inference unveil dynamics of cell activation, survival and crosstalk in Chronic Lymphocytic Leukaemia in vitro models

Malvina Marku, Hugo Chenel, Julie Bordenave…·Véra Pancaldi

The paper uses time-series RNA-Seq and gene regulatory network inference to study how CLL cells respond to immune signals in vitro, revealing dynamic regulatory mechanisms and patient-specific gene modules.

DOI 10.1101/2025.04.20.649300

humanbulk RNA-seq

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