Staphylococcal Internalization into Osteoblasts: A Partially Conserved Mechanism Across the Genus
Deborah M. Crepin, Mélanie Bonhomme, Allison Faure, Clara Sinel, Marine Bergot, Virginie Dyon-Tafani, Yousef Maali, Daniel Bouvard, Alan Diot, Frederic J. Laurent, Jérôme Josse
This study investigates the internalization of staphylococci into osteoblasts across the genus, finding that half of the species can invade these cells via a conserved FnBP-fibronectin-5β1 integrin pathway.
mBio · Dec 16, 2025Peer-reviewedMicrobiology