Synthetic BiologybioRxivPreprint
Rational mRNA Structure -guided Attenuation Enables Embryo-safe in-ovo NDV Vaccination and Protection
Tamir Tuller, Zohar Zafrir, Dana Goldenberg…·Modi Roopin
The paper develops an embryo-safe NDV vaccine by using structure-aware synonymous mutations to modulate RNA folding, achieving high hatchability and protection against NDV challenge.
DOI 10.64898/2026.09.29.755556