BioinformaticsbioRxivPreprint
sciLaMA: A Single-Cell Representation Learning Framework to Leverage Prior Knowledge from Large Language Models
Hongru Hu, Shuwen Zhang, Yongin Choi…·Gerald Quon
sciLaMA integrates gene embeddings from large language models with scRNA-seq data using a paired-VAE architecture, improving downstream tasks like batch correction and clustering while maintaining computational efficiency.
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