Genetic & Genomic MedicinemedRxivPreprint
A lifespan transcriptomic atlas of the human prefrontal cortex at single-cell resolution
Hui Yang, Tereza Clarence, Madeline R. Scott…·Panos Roussos
This study creates a single-nucleus transcriptomic atlas of the human DLPFC across the lifespan, revealing three transcriptomic phases and ten age-related trajectories linked to neurodevelopmental and neurodegenerative disease risk.