BioinformaticsbioRxivPreprint
A Two-Stage ESM-Based Machine Learning Pipeline for Robust Hierarchical Enzyme Function Prediction
Xiao Hua, Ghjuvan Micaelu Grimaud
ESM-ECForest uses ESM-2 embeddings and Random Forest classifiers to predict enzyme functions with high accuracy across EC levels.
DOI 10.64898/2026.08.14.744831