Author

Harald Melin

KTH Royal Institute of TechnologyORCID 0009-0007-7157-6479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1

Frequent Co-Authors

Jens LagergreniD· 2 shared Vittorio ZampinettiiD· 2 shared Alva Hallin· 1 shared Andrew McPhersoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersCancer Biology

Jens LagergrenORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 31, 2026

Scalable and robust phylogenetic tree reconstruction from copy-number data with Sparse Rooted Neighbor Joining

Vittorio Zampinetti, Harald Melin, Alva Hallin, Jens Lagergren

This paper introduces SRNJ, a scalable rooted Neighbor Joining method for phylogenetic tree reconstruction from copy-number data, showing improved accuracy and efficiency over standard NJ.

DOI 10.64898/2026.07.30.739152

DNA methylationwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologyLecture notes in computer sciencePeer-reviewedJan 1, 2024

VICTree - a Variational Inference method for Clonal Tree reconstruction

Harald Melin, Vittorio Zampinetti, Andrew McPherson, Jens Lagergren

VICTree is a variational inference method for clonal tree reconstruction that uses a Tree-structured Mixture Hidden Markov Model and evaluates on cancer datasets.

5 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky