ImmunologybioRxivPreprint
Quantifying the Recoverability of V and J Genes from TCR CDR3 Sequences Using Generative Repertoire Models
SAMUEL F. HUANG, Alexander Spyridon Baras
This paper quantifies how much V and J gene identity can be recovered from TCR CDR3 sequences using generative models and shows that J genes are nearly determined while V genes are partially recoverable with group-level structure.