Author

Elaine Byrnes

University of PittsburghORCID 0009-0007-7553-1403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aatur Dilip SinghiiD· 1 shared Rajdeep Pawar· 1 shared Rebecca Raphael· 1 shared Shikhar UttamiD· 1 shared Simon C. WatkinsiD· 1 shared Thing Rinda SoongiD· 1 shared Thomas Jacob· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Aatur Dilip SinghiORCID

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1 paper

Recent·Most cited

Systems BiologybioRxivPreprintSep 29, 2026

SpaReg: sparsity-based 3D reconstruction of tissue microenvironments at native resolution across morphological and spatial molecular modalities

Rajdeep Pawar, Thomas Jacob, Rebecca Raphael…·Shikhar Uttam

SpaReg reconstructs 3D tissue microenvironments from histology, spatial proteomics, and spatial transcriptomics data, preserving morphology and enabling accurate classification and disease modeling.

DOI 10.64898/2026.09.28.754175

humanspatial transcriptomics

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