BioinformaticsbioRxivPreprint
BrainSTEM: A multi-resolution fetal brain atlas to assess the fidelity of human midbrain cultures
Hilary S. Y. Toh, Lisheng Xu, Carissa Chen…·John F. Ouyang
The paper introduces BrainSTEM, a multi-resolution mapping framework to evaluate midbrain differentiation protocols by comparing them to a fetal brain atlas, revealing off-target cell types in most published models.