Author

William T. Longstreth Jr.

University of WashingtonORCID 0009-0007-9552-3603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:whole-genome sequencing· 2 Assay:GWAS summary statistics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexa BeiseriD· 2 shared Bruce M. PsatyiD· 2 shared Charles S DeCarliiD· 2 shared Eric BoerwinkleiD· 2 shared Jerome I. RotteriD· 2 shared Joshua C. BisiD· 2 shared Lenore J. LauneriD· 2 shared Myriam FornageiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alexa BeiserORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 11, 2025

Whole genome sequence association analysis of brain structural volume measures in the NHLBI TOPMed Program highlights novel loci in diverse participants

Lincoln M. P. Shade, Mohsen Sharifitabar, Alexa Beiser…·Chloé Sarnowski

This study uses whole-genome sequence data from diverse participants to identify novel genetic loci associated with brain structural volumes, highlighting the importance of diverse cohorts in uncovering genetic architecture.

DOI 10.1101/2025.06.11.25329426

humanwhole-genome sequencing

Genetic & Genomic MedicineNature GeneticsPeer-reviewedOct 21, 2024

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

Luis M. García‐Marín, Adrián I. Campos, Santiago Díaz‐Torres…·Michelle Luciano A

The paper conducts GWAS on brain volumes, identifies genetic loci, and develops polygenic scores with cross-ancestry predictive ability and causal links to neuropsychiatric disorders.

25 citationstop 2%

humanGWAS summary statistics

Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedJun 12, 2021

BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportion

Tamar Sofer, Jiwon Lee, Nuzulul Kurniansyah…·Elizabeth D. Schifano

The paper introduces BinomiRare, a test for rare variant association with binary outcomes in mixed models, showing it controls type 1 error in simulations and applies it to study genetic variants in disease traits.

5 citations

humanwhole-genome sequencing