Alexa Beiser

The paper identifies plasma proteins associated with diffusion tensor imaging biomarkers of white matter injury and suggests potential causal relationships using Mendelian randomization.

This study shows that gut microbiota mediates the effect of APOE ε4 genotype on amyloid-β accumulation in middle-aged adults.

This study shows that better adherence to LE8 metrics improves gut microbiota diversity and cognitive performance in the Framingham Heart Study participants.

This study uses whole-genome sequence data from diverse participants to identify novel genetic loci associated with brain structural volumes, highlighting the importance of diverse cohorts in uncovering genetic architecture.

The paper conducts GWAS on brain volumes, identifies genetic loci, and develops polygenic scores with cross-ancestry predictive ability and causal links to neuropsychiatric disorders.

This study identifies 67 genetic loci associated with head size, finding strong overlaps with cancer pathways and genes, suggesting shared genetic mechanisms between head growth and cancer risk.

This study identifies three novel genetic loci associated with brain arterial diameters through a genome-wide association analysis across diverse populations.

The paper investigates the relationship between gut microbiota and cerebral small vessel disease markers in the Framingham Heart Study, finding associations between specific bacterial genera and cSVD burden.

The paper analyzes de novo mutations in 1,465 genomes to show similar mutation rates across ancestries but reduced rates in the Amish population, with environmental factors possibly influencing mutation rates.

This study identifies genetic loci specific to periventricular and deep white matter hyperintensities, revealing distinct genetic architectures and potential biological mechanisms.

The paper identifies 161 genome-wide significant genetic associations for cortical structure traits across 34 brain regions, highlighting key biological pathways and gene functions.

Genetic correlations across 25 brain disorders (215,683 cases) reveal broad psychiatric common-variant sharing, largely distinct neurological disorders, and migraine as the only significant cross-category link.