BioinformaticsbioRxivPreprint
ProtFlow: Flow Matching-based Protein Sequence Design with Comprehensive Protein Semantic Distribution Learning and High-quality Generation
Zitai Kong, Yiheng Zhu, Yinlong Xu…·Chang‐Yu Hsieh
ProtFlow generates high-quality protein sequences by learning the full semantic distribution of protein space, outperforming existing methods in generating antimicrobial peptides with broad activity.