scGPT-spatial: Continual Pretraining of Single-Cell Foundation Model for Spatial Transcriptomics
Chloe Xueqi Wang, Haotian Cui, Andrew Zhang, Ronald Xie, Hani Goodarzi, Bo Wang
Further pretraining a single-cell foundation model on 30 million spatial profiles, with a protocol-aware mixture-of-experts decoder and a neighbourhood objective, supports multi-slide integration, deconvolution and imputation.
bioRxiv · Feb 5, 2025 · PreprintBioinformatics