Author

Andrew Zhang

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:deep learning· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Adit Shah· 1 shared Alex Beatson· 1 shared Andreas BenderiD· 1 shared Ángel Alexander CabreraiD· 1 shared Anna Halpin-McCormickiD· 1 shared Anne Elizabeth CarpenteriD· 1 shared Beilei BianiD· 1 shared Boxiang LiuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioinformatics

Adit Shah

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Author profile →

4 papers

Recent·Most cited

Generalisable tissue-wide molecular reconstruction from histology

Andrew Zhang, Lijia Yu, Beilei Bian, Yue Cao, Shuchang Ye, Ethan Han, Harry Robertson, Yan Dong, Yixiao Mao, Boxiang Liu, Ellis Patrick, Jinman Kim, Jean Yee Hwa Yang

GHIST+ reconstructs tissue-wide molecular maps from H&E histology, enabling cohort-scale molecular reconstruction from sparse spatial transcriptomic data.

bioRxiv · Jun 12, 2026 · PreprintBioinformatics

Unlocking the potential of Capsicum Germplasm Collections for Climate Resilience and Fruit Quality

Anna Halpin-McCormick, Manoj Kumar Nalla, Zachary Radlicz, Andrew Zhang, Nathan Fumia, Tsung-Han Lin, Shih-wen Lin, Yen-wei Wang, Herbaud P. F. Zohoungbogbo, Diane Wang, Bryan C. Runck, Michael A. Gore, Michael Benjamin Kantar, Derek W. Barchenger

This paper develops a framework combining genomic prediction and a large language model to select climate-resilient pepper cultivars from germplasm collections.

bioRxiv · Mar 28, 2026 · PreprintPlant Biology

Glycerol-3-phosphate activates ChREBP, FGF21 transcription and lipogenesis in Citrin Deficiency

Vinod Tiwari, Byungchang Jin, Olivia Sun, Edwin D. J. Lopez Gonzalez, Min-Hsuan Chen, Xiwei Wu, Hardik Shah, Andrew Zhang, Mark A. Herman, Cassandra Nichole Spracklen, Russell P. Goodman, Charles Brenner

This study identifies G3P-ChREBP as a mechanism linking Citrin Deficiency to metabolic dysfunction by activating FGF21 and lipogenesis, affecting food and alcohol choices.

Nature Metabolism · Nov 14, 2025Peer-reviewedMolecular Biology

Small molecule bioactivity benchmarks are often well-predicted by counting cells

Srijit Seal, William Dee, Adit Shah, Andrew Zhang, Katherine Titterton, Ángel Alexander Cabrera, Daniil A. Boiko, Alex Beatson, Jordi Carreras Puigvert, Shantanu Singh, Ola Spjuth, Andreas Bender, Anne Elizabeth Carpenter

The paper shows that cell counting can predict compound bioactivity as well as Cell Painting or gene expression, but Cell Painting adds unique value in protein-target-specific benchmarks.

bioRxiv · Apr 27, 2025 · PreprintBioinformatics