Synthetic BiologybioRxivPreprint
Computational pipeline for targeted integration and variable payload expression for bacteriophage engineering.
Jonas Fernbach, Emese Hegedis, Martin J. Loessner, Samuel Kilcher
The paper develops a computational pipeline to integrate antimicrobial payloads into bacteriophages by identifying optimal genomic loci using machine learning, validated experimentally with bioluminescent reporter genes.
DOI 10.1101/2024.06.17.597714