Evolutionary BiologybioRxivPreprint
Universal genomic constraints in the evolvability of thermal physiology
Brian P Waldron, Eliza Tarimo, Palash Sashittal…·Josef C. Uyeda
The paper uses simulations to show that body temperature evolution is constrained by protein thermal performance, leading to predictable patterns of rapid initial change followed by slow adaptation.
DOI 10.64898/2025.12.12.693958