Author

Xavier Soler Sanchis

Barcelona Institute of Science and TechnologyORCID 0009-0008-5717-2002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Charles W. J. PughiD· 1 shared Ezequiel Alejandro GalperniD· 1 shared Federico BilleciiD· 1 shared Jonathan FrazeriD· 1 shared Mafalda DiasiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Charles W. J. PughORCID

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1 paper

Recent·Most cited

Blending physics-based and inverse folding models to disentangle variant effects on stability and function

Ezequiel Alejandro Galpern, Xavier Soler Sanchis, Charles W. J. Pugh, Federico Billeci, Jonathan Frazer, Mafalda Dias

The paper blends physics-based and inverse folding models to separate variant effects on protein stability and function, revealing distinct signatures for gain-of-function and loss-of-function variants.

bioRxiv · Aug 4, 2026 · PreprintBiophysics