ImmunologybioRxivPreprint
Uncertainty-aware quantitative analysis of the structure and dynamics of T cell receptor repertoires
Simo Kitanovski, Kai Wollek, Daniel E. Hoffmann
This paper introduces ClustIRR, a framework for analyzing T cell receptor repertoire structure and dynamics with uncertainty quantification, demonstrating its application in antigen challenge, cancer immunotherapy, and V(D)J recombination biases.