Pharmacology & ToxicologybioRxivPreprint
Divergent Side-Chain Networks of the Mineralocorticoid Receptor Control Mutation-Altered Drug Response
Johannes Jokiel, Marcel Bermúdez
This study uses molecular dynamics simulations to show how the S810L mutation in the MR alters ligand-specific agonist/antagonist behavior by changing side-chain network interactions.
DOI 10.64898/2025.12.18.695081