Cancer BiologybioRxivPreprint
Functional T cells trapped behind a stromal wall: a Brake-with-Wall phenotype redefines pancreatic adenocarcinoma immunotherapy resistance
This paper redefines pancreatic adenocarcinoma immunotherapy resistance by identifying a 'Brake-with-Wall' phenotype where functional T cells are trapped behind a fibroblast wall, suggesting that triple-targeted intervention may be needed.
DOI 10.64898/2026.05.11.724216