Author

John J. Brewington

Cincinnati Children's Hospital Medical CenterORCID 0009-0008-9190-8087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Pion· 1 shared Alicia J. Ostmann· 1 shared Ana Topasna· 1 shared Garry R. CuttingiD· 1 shared Georgia Kelly· 1 shared Jessica D. Meeker· 1 shared Karen S. RaraighiD· 1 shared Kristen A. MilleriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

A. Pion

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintJun 18, 2026

Clinical and primary cell evidence reveals complex CFTR function-phenotype relationships

Kristen A. Miller, A. Pion, Ana Topasna…·Karen S. Raraigh

The paper integrates clinical and primary cell data to show the CFTR function-phenotype relationship is logarithmic, not linear, with greater phenotypic gains at lower baseline function.

DOI 10.64898/2026.06.17.732921

humanbulk RNA-seq

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