Author

A. Pion

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Neeraj SharmaiD· 3 shared Alice C. EastmaniD· 2 shared Ana Topasna· 2 shared Erin W. KavanaghiD· 2 shared Garry R. CuttingiD· 2 shared K. Starego· 2 shared Karen S. RaraighiD· 2 shared Alianna I. Parr· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Neeraj SharmaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clinical and primary cell evidence reveals complex CFTR function-phenotype relationships

Kristen A. Miller, A. Pion, Ana Topasna, Alicia J. Ostmann, Jessica D. Meeker, Georgia Kelly, John J. Brewington, Neeraj Sharma, Garry R. Cutting, Karen S. Raraigh

The paper integrates clinical and primary cell data to show the CFTR function-phenotype relationship is logarithmic, not linear, with greater phenotypic gains at lower baseline function.

bioRxiv · Jun 18, 2026 · PreprintGenetics

CFTR function in nasal airway cells from symptomatic and asymptomatic CF heterozygotes

A. Pion, Alyssa Chang, Piero Mejia, Alice C. Eastman, Erin W. Kavanagh, Ana Topasna, K. Starego, Alianna Parr, Karen S. Raraigh, Christian Merlo, Neeraj Sharma, Garry Cutting

This study measures CFTR function in nasal airway cells from CF heterozygotes and controls, finding reduced CFTR activity in heterozygotes regardless of symptoms.

bioRxiv · Jun 18, 2026 · PreprintGenetics

Base editing and nanoparticle transfection of airway cell types essential for treatment of cystic fibrosis

Erin W. Kavanagh, Anya T. Joynt, A. Pion, Alice C. Eastman, Alianna I. Parr, K. Starego, Manav Jain, Sydney R. Shannon, Edwin Yoo, Gregory A. Newby, Stephany Yi Tzeng, Neeraj Sharma, Jordan J. Green, Garry R. Cutting

This study corrects a CFTR splice site variant in airway cells using base editors and nanoparticles, showing increased CFTR expression and functional rescue in multiple cell types.

JCI Insight · May 7, 2026Peer-reviewedGenetics