BiophysicsbioRxivPreprint
Danuglipron and orforglipron engage GLP-1R through materially different interfaces: an unbiased molecular dynamics study
This study uses molecular dynamics to show that danuglipron and orforglipron bind GLP-1R through distinct interfaces, with different contact distributions and occupancy patterns.
DOI 10.64898/2026.09.30.754652