Author

Mary E. Likhite

University of Massachusetts Chan Medical SchoolORCID 0009-0009-1515-257XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Anshul Bharat KundajeiD· 1 shared Gregory AndrewsiD· 1 shared Jill E. MooreiD· 1 shared Mingshi GaoiD· 1 shared Vivekanandan RamalingamiD· 1 shared Vivian C. HechtiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperGenomics

Anshul Bharat KundajeORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJul 20, 2026

Architectural chromatin interactions provide a framework for context-dependent gene regulation

Mary E. Likhite, Gregory Andrews, Mingshi Gao…·Jill E. Moore

The paper develops an integrative framework to classify and interpret promoter-centric chromatin interactions by combining Hi-C, ChIA-PET, and functional genomic data, identifying a distinct class of architectural promoter-enhancer interactions with context-dependent regulatory roles.

DOI 10.64898/2026.07.17.739237

humanHi-C

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