BioinformaticsbioRxivPreprint
How many cells resolve a perturbation direction? A closed-form, control-aware cell quota for single-cell perturbation screens
Loc Thai Huu Tran, Van Thi Nguyen
The paper derives a closed-form cell quota to determine the number of cells needed to accurately estimate perturbation direction in single-cell screens, validated across multiple datasets.
DOI 10.64898/2026.10.02.754788