Author

Shiri Jaffe‐Herman

Hebrew University of JerusalemORCID 0009-0009-2297-1055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Aveksha SharmaiD· 3 shared Eden EngaliD· 3 shared Gillian KayiD· 3 shared Maayan SaltoniD· 3 shared Mercedes Bentata· 3 shared Ophir GeminderiD· 3 shared Adi Gershon· 2 shared Mai BakeriD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Aveksha SharmaORCID

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3 papers

Recent·Most cited

Molecular BiologyRNAPeer-reviewedDec 24, 2025

SF3B1K700E rewires splicing of cell-cycle regulators

Mai Baker, Eden Engal, Aveksha Sharma…·Maayan Salton

The paper identifies SF3B1K700E-induced splicing changes in K562 cells that affect cell cycle regulators, with functional consequences in mitosis and cancer survival.

DOI 10.1261/rna.080661.125

humanbulk RNA-seq

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GenomicsScience AdvancesPeer-reviewedMay 29, 2024

SMCHD1 loss triggers DUX4 expression by disrupting splicing in FSHD2

Eden Engal, Aveksha Sharma, Uria Aviel…·Yotam Drier

This study shows SMCHD1 loss causes DUX4 expression in FSHD2 by disrupting splicing of DNMT3B, leading to hypomethylation and muscle abnormalities.

9 citations

humanbulk RNA-seq

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Molecular BiologyPLoS BiologyPeer-reviewedJun 28, 2023

Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth

Aveksha Sharma, Shani Mistriel-Zerbib, Rauf Ahmad Najar…·Maayan Salton

This study investigates the roles of TAL1 isoforms in hematopoiesis and cell growth, finding that TAL1-short promotes apoptosis and can act as a tumor suppressor.

14 citations

mouseproteomics

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