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S. C. Chen

ByteDance (China)ORCID 0009-0009-2566-7526Unclaimed ORCID profile · follow to get notified of new preprints

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S. C. Chen1 paper

Biology Disciplines

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Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:protein structure prediction· 1 Approach:variational autoencoder· 1

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Fengyu Yang· 1 shared Haibin LingiD· 1 shared Jing YuaniD· 1 shared Quanquan GuiD· 1 shared Shahar Z. KovalskyiD· 1 shared Xiaoqing ZhengiD· 1 shared Yi ZhouiD· 1 shared Yilai LiiD· 1 shared

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1 shared paperBiophysics

Fengyu Yang

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1 paper

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BiophysicsbioRxivPreprintDec 29, 2025

A Generative Foundation Model for Cryo-EM Densities

Yilai Li, Jing Yuan, Yi Zhou…·Quanquan Gu

This paper introduces cryoFM, a generative foundation model for cryo-EM densities that improves reconstruction and refinement by combining data-driven priors with dataset-specific constraints.

DOI 10.64898/2025.12.29.696802

cryo-EMdeep learning

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