Evolutionary BiologybioRxivPreprint
Gene Interaction Network Architecture of Human Polygenic Traits Reveals Domain-Specific Connectivity and Evolutionary Pressures
Ehsan Tamandeh, Jessica Bigge, Adrian W.R. Serohijos…·Pouria Dasmeh
The paper analyzes gene interaction networks across polygenic traits, finding higher connectivity in trait-associated genes and weaker selective constraints in highly connected networks, and develops an online portal for hypothesis generation.
DOI 10.1101/2025.05.23.655809