Synthetic BiologyGenome ResearchPeer-reviewed
Deep learning of the regulatory grammar of yeast 5’ untranslated regions from 500,000 random sequences
Josh T. Cuperus, Benjamin Groves, Anna Kuchina…·Georg Seelig
The paper trains a CNN to predict translational efficiency of yeast 5' UTRs using synthetic sequences and validates it on native sequences and evolved designs.
212 citations