Author

Magdalena Otto

University of ViennaORCID 0009-0009-7714-0646Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 1

Frequent Co-Authors

Thomas A. LeonardiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJul 29, 2026

Dimerization-dependent cis-autophosphorylation activates the UPR and ISR kinases

Magdalena Otto, Thomas A. Leonard

This study identifies dimerization-dependent cis-autophosphorylation as the mechanism activating UPR and ISR kinases, showing it is necessary and sufficient for PERK activation.

1 citation

statistical model

𝕏 PostBluesky