Author

Laura B Dillon

University of OxfordORCID 0009-0009-9186-5846Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1

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Aaron MaiwaldiD· 1 shared Oliver M. CrookiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Aaron MaiwaldORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintOct 21, 2025

Decoding the physicochemical basis of taxonomy preferences in protein design models

Laura B Dillon, Oliver M. Crook, Aaron Maiwald

This study examines how scoring context and training data influence protein design models' preferences across species, showing that backbone-conditioned models favor archaeal and thermophilic proteins while sequence-only models favor eukaryotic proteins.

1 citation

protein sequencedeep learning

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