Molecular BiologyNature CommunicationsPeer-reviewed
Directionality of Transcriptional Regulatory Elements
You Chen, Sagar R Shah, Alden King-Yung Leung…·Haiyuan Yu
This study compares divergent and unidirectional transcriptional regulatory elements, finding that unidirectional elements are younger and less constrained, with some transcription factors modulating their directionality.
DOI 10.1038/s41467-026-76415-5