Author

Chris Sebastian

University of PennsylvaniaORCID 0009-0009-9453-8816Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jin JiniD· 1 shared Mengxin YuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperGenetic & Genomic Medicine

Jin JinORCID

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1 paper

Recent·Most cited

Genetic & Genomic MedicineBriefings in BioinformaticsPeer-reviewedSep 1, 2026

Constructing a Literature-Derived Database for Benchmarking Polygenic Risk Score Construction Methods with Spectral Ranking Inferences

Chris Sebastian, Mengxin Yu, Jin Jin

This study constructs a literature-derived database to benchmark polygenic risk score methods using spectral ranking, identifying top and bottom performers and providing phenotype-specific insights.

DOI 10.1093/bib/bbag598

humanGWAS summary statistics

𝕏 PostBluesky