Author

Monireh Safari

University of WaterlooORCID 0009-0009-9800-0108Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Lila Kari AiD· 2 shared Gurjit S. RandhawaiD· 1 shared Joseph ButleriD· 1 shared Kathleen Allen HilliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBioinformatics

Lila Kari AORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 17, 2026

Beyond phylogeny: Genome-wide DNA sequence patterns suggest DNA physical properties associated with thermal adaptation in extremophile microbes

Monireh Safari, Lila Kari A

The paper identifies DNA sequence patterns associated with thermal adaptation in extremophiles, independent of phylogeny, using structural topic modelling of short sequence motifs.

DOI 10.64898/2026.06.16.732181

bacteria (other)virus

𝕏 PostBluesky

BioinformaticsNAR Genomics and BioinformaticsPeer-reviewedOct 7, 2025

Life at the extremes: Maximally divergent microbes with similar genomic signatures linked to extreme environments

Monireh Safari, Joseph Butler, Gurjit S. Randhawa…·Lila Kari A

The paper identifies 15 bacterium-archaeon pairs with similar genomic signatures despite maximal taxonomic divergence, showing environmental pressures drive convergent genome-wide patterns.

1 citation

bacteria (other)whole-genome sequencing

𝕏 PostBluesky