bioRxivScientific Communication & EducationPreprint
Current challenges in microbiome metadata collection
Abstract
While the biomedical community has embraced data sharing (e.g. results, raw data) and supported establishment of large research consortia (e.g. the Human Microbiome Project) aimed to standardize the quality of important sets of microbiome sequencing data, the reusability of most microbiome data is still limited by the quality of its associated metadata. To ensure that microbiome data is indeed FAIR (Findable, Accessible, Interoperable, and Reusable), it is necessary to consider tools and approaches that make it easier to provide high-quality metadata that is fit for purpose moving forward. Such tools and approaches could be informed by current efforts to harmonize and improve the quality of extant microbiome metadata.
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Tier-based standards for FAIR sequence data and metadata sharing in microbiome research
Lina Kim, Anton Lavrinienko, … Nicholas A. Bokulich·Nucleic Acids ResearchPeer-reviewed·Jul 28, 2025
- BioSharing: Harnessing Metadata Standards For The Data Commons
Susanna-Assunta Sansone, Alejandra Gonzalez-Beltran, … Milo Thurston·bioRxiv·May 31, 2017
- A roadmap for fair reuse of public microbiome data
Laura A. Hug, Roland Hatzenpichler, … Matthew Kellom·Nature MicrobiologyPeer-reviewed·Sep 26, 2025
- From Public Archive to Reusable Resource: Characterizing Gut Microbiome Metadata in the NCBI SRA
Kiersten Oderman, Tarak Nandi, … Jarrad Hampton‐Marcell·bioRxiv·Oct 2, 2026
- Developing a standardized but extendable framework to increase the findability of infectious disease datasets
Ginger Tsueng, Marco Alvarado Cano, … Serdar Turkarslan·Scientific DataPeer-reviewed·Feb 23, 2023
- FAIR enough? A perspective on the status of nucleotide sequence data and metadata on public archives
Christiane Hassenrück, Tobias Poprick, … Ivaylo Kostadinov·bioRxiv·Sep 23, 2021