LLM-Evolved Regularization Schedules Prevent Posterior Collapse in Latent Factor Analysis via Dynamical Systems
Abstract
Latent Factor Analysis via Dynamical Systems (LFADS) is a powerful variational autoencoder for inferring neural population dynamics from spike train data. However, LFADS suffers from pos-terior collapse, where the learned posterior collapses to the prior, eliminating meaningful latent representations. Current solutions require computationally expensive Population-Based Training (PBT) to dynamically tune regularization hyperparameters. Here, we demonstrate that Large Lan-guage Model (LLM)-based program evolution can discover regularization schedules that prevent posterior collapse without PBT. Using FunSearch, an evolutionary algorithm that uses LLMs to generate and refine Python functions, we evolved adaptive regularization schedules that respond to training dynamics. Our best evolved schedule prevents posterior collapse across all tested conditions, maintaining KL divergence 6.5x higher than baseline schedules at 50 epochs (n = 10 seeds each, p < 0.001) and stable above 0.09 through 500 epochs across three Neural Latents Benchmark datasets, while preserving reconstruction quality. This work represents the first application of LLM-based program synthesis to variational autoencoder hyperparameter scheduling, offering a computationally efficient alternative to population-based optimization.
02 /Specification & Classification
Click any tag to browse matching papers- Citations
- 0
- Research Focus
- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Inferring single-trial neural population dynamics using sequential auto-encoders
Chethan Pandarinath, Daniel J. O’Shea, … David Sussillo·Nature MethodsPeer-reviewed·Sep 14, 2018
- A large-scale neural network training framework for generalized estimation of single-trial population dynamics
Mohammad Reza Keshtkaran, Andrew R. Sedler, … Chethan Pandarinath·Nature MethodsPeer-reviewed·Nov 28, 2022
- Scalable Bayesian GPFA with automatic relevance determination and discrete noise models
Kristopher Torp Jensen, Ta-Chu Kao, … Guillaume Hennequin·bioRxiv·Jun 3, 2021
- iLQR-VAE : control-based learning of input-driven dynamics with applications to neural data
Marine Schimel, Ta-Chu Kao, … Guillaume Hennequin·bioRxiv·Oct 7, 2021
- Discovering Temporally Compositional Neural Manifolds with Switching Infinite GPFA
Changmin Yu, Maneesh Sahani, Máté Lengyel·bioRxiv·Oct 4, 2024
- Thoughts-as-Planning: Latent World Models for Chain-of-Thoughts Optimization via Reinforcement Planning
Dong Liu, Yang Yu, Ying Nian Wu·bioRxiv·May 15, 2026