Aperiodic and oscillatory systems underpinning human domain-general cognition

Abstract

Domain-general cognitive systems are essential for adaptive human behaviour, supporting various cognitive tasks through flexible neural mechanisms. While fMRI studies link the frontoparietal network activation to increasing demands across various tasks, the electrophysiological mechanisms underlying this domain-general response to demand remain unclear. Here, we used MEG/EEG, with aperiodic and oscillatory components separated, to examine their roles in domain-general cognition across three cognitive tasks using multivariate analysis. We found that both aperiodic (broadband power, slope, and intercept) and oscillatory (theta, alpha, and beta power) components coded task demand and content across all subtasks. Aperiodic broadband power in particular strongly coded task demand, in a manner that generalised across all subtasks. Source estimation suggested that increasing cognitive demand decreased aperiodic broadband power across the brain, with the strongest modulations overlapping with the frontoparietal network. In contrast, oscillatory activity showed more localised patterns of modulation, primarily in frontal or occipital regions. These results provide insights into the electrophysiological underpinnings of human domain-general cognition, highlighting the critical role of aperiodic broadband power.