SRY: An Effective Method for Sorting Long Reads of Sex-limited Chromosome

Abstract

Most of available reference genomes are lack of the sequence map of sex-limited chromosomes, that make the assemblies uncompleted. Recent advances on long reads sequencing and population sequencing raise the opportunity to assemble sex-limited chromosomes without the traditional complicated experimental efforts. We introduce a computational method that shows high efficiency on sorting and assembling long reads sequenced from sex-limited chromosomes. It will lead to the complete reference genomes and facilitate downstream research of sex-limited chromosomes.