Kevin H.-C. Wei

The paper investigates non-Mendelian transmission of recombinants in female meiosis, showing that chromatids with crossovers have a transmission advantage under nutrient stress in Drosophila.

The paper studies a young Y chromosome in Drosophila albomicans that recombines with the X chromosome before recombination shutdown, maintaining long-range linkage without inversions.

The paper introduces DemuxHMM, a recombination-aware demultiplexing method that improves scalability and performance for large-scale single-cell embryo profiling.

The paper investigates how polymorphic transposable elements (TEs) influence meiotic recombination rates in Drosophila by analyzing crossover frequencies in strains with distinct TE profiles.

The paper tests a candidate meiotic drive locus in Drosophila melanogaster using individual progeny genotyping, finding a small deviation from Mendelian segregation opposite to initial pool sequencing results.

The paper maps H3K9me3-dependent heterochromatin formation in Drosophila miranda embryos, showing early nucleation at transposable elements and piRNA-mediated silencing.

This paper introduces a method to estimate chromosome-wide recombination rates using marker selected pools and validates it with simulations and empirical data.

The paper assembles the Drosophila miranda Y chromosome using long reads and chromatin conformation capture, revealing its expansion through repetitive sequences.

The paper develops a pooled sequencing method to detect meiotic drivers in Drosophila and identifies a candidate driver in a centromere-linked region with an 8% increased transmission frequency.