Sequence Characterization Of Glutamate Receptor Genes Of Rat A Vertebrate And Arabidopsis Thaliana A Plant
Antara SenguptaiD, Pabitra Pal ChoudhuryiD, Subhadip Chakraborty
Abstract
iGluR gene family of a vertebrate, Rat and AtGLR gene family of a plant, Arabidopsis thaliana [4] perform some common functionalities in neuro-transmission, which have been compared quantitatively. Our attempt is based on the chemical properties of amino acids [6, 7, 8] comprising the primary protein sequences of the aforesaid genes. 19 AtGLR genes of length varying from 808 amino acid (aa) to 1039 aa and 16 iGluR genes length varying from 902aa to 1482 aa have been taken as data sets. Thus, we detected the commonalities (conserved elements) during the long evolution of plants and animals from a common ancestor [4]. Eight different conserved regions have been found based on individual amino acids. Two different conserved regions are also found, which are based on chemical groups of amino acids. We have tried too to find different possible patterns which are common throughout the data set taken. 9 such patterns have been found with size varying from 2 to 5 amino acids at different regions in each primary protein sequences. Phylogenetic trees of AtGLR and iGluR families have also been constructed. This approach is likely to shed light on the long course of evolution.
02 /Specification & Classification
Click any tag to browse matching papers- Citations
- 1
- Organism
- Assay
- Research Focus
- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain
S. P. Gangwar, M. Green, A. Sobolevsky·bioRxiv·Dec 23, 2019
- One Molecule, Multiple Histories: Comparative Phylogenomics of Glutamate Metabolism, Transport and Receptor Families Across 89 Eukaryotic Proteomes
ANKIT THAKUR, Mahesh Kulharia·bioRxiv·Sep 10, 2026
- Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan Epsilon receptor
Anhadvir Singh, Boris S. Zhorov, … Adriano Senatore·Communications BiologyPeer-reviewed·Jul 3, 2025
- A putative origin of insect chemosensory receptors in the last common eukaryotic ancestor
R. Benton, C. Dessimoz, D. Moi·bioRxiv·Aug 24, 2020
- Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain
S. Seljeset, O. Sintsova, … T. Lynagh·bioRxiv·Aug 3, 2023
- Ionotropic glutamate receptors in the retina - a bioinformatical meta-analysis
Bianca Pircher, Thomas Pircher, Andreas Feigenspan·bioRxiv·Nov 27, 2021